GLOCK 21 V MOS .45 ACP 4.60in Black (3) 13-Rd

$726.84

Full-size .45 ACP with MOS optics cut, Glock Marksman Barrel, three 13-round magazines, and modular backstraps—ready for red dots out of the box at $648.96.

Available for delivery across the United States.

SKU: CSSI|GLUV2150203MOS Category:

Description

GLOCK 21 V MOS .45 ACP 4.60in Black (3) 13-Rd

The GLOCK 21 V MOS .45 ACP 4.60in Black (3) 13-Rd is a full-size, optics-ready semi-auto handgun built for shooters who demand .45 ACP stopping power with modern red dot capability. It pairs a 4.60-inch Glock Marksman Barrel with an MOS-cut slide, three 13-round magazines, and a black polymer frame with an integral accessory rail. Fixed sights deliver a clean sight picture out of the box, while modular backstraps let you dial in the grip. Per GLOCK specs, the slide is serrated for positive manipulation under any condition.

Manufacturer GLOCK
Model 21 V MOS Gen4
Material Polymer frame, steel slide
Compatibility MOS-series optics (Trijicon RMR, Holosun 407C/507C, etc.)
Finish Black nDLC slide, black polymer frame
Weight 26.28 oz (unloaded, per manufacturer specs)
Condition New

Key Features

  • MOS Optics-Ready Slide — The Modular Optic System cut accepts over a dozen micro red dots without aftermarket milling, letting you co-witness with the fixed sights. Why it matters: you can switch between iron sights and a red dot without sending the slide to a gunsmith.
  • Glock Marksman Barrel (GMB) — Enhanced rifling and a polished chamber improve accuracy over previous GLOCK barrels. Why it matters: you’ll hold tighter groups at 25 yards, especially with defensive .45 ACP loads.
  • Three 13-Round Magazines — Full capacity for a .45 ACP duty pistol, with a steel-reinforced polymer body and orange follower for easy round counts. Why it matters: you get 39 rounds total out of the box—enough for a class, a match stage, or a nightstand reload.
  • Modular Backstrap System — Interchangeable backstraps (standard, medium, large) let you adjust the grip circumference. Why it matters: shooters with smaller or larger hands get a natural point of aim without buying a custom frame.
  • Integral Accessory Rail — The GLOCK-pattern rail fits lights and lasers from SureFire, Streamlight, and others. Why it matters: you can mount a weapon light for low-light identification without adapter plates.

Who It’s For

The GLOCK 21 V MOS is built for shooters who want .45 ACP terminal performance with the speed of a red dot. It fits competition shooters shooting USPSA Single Stack or Limited Optics, law enforcement officers who need a duty-size .45, and home defenders who want a full-grip handgun with nightstand reliability. If you’ve been running iron sights on a .45 and want to step into the red dot world without buying a new slide, this is your platform.

Pros & Cons

  • Pro: MOS cut lets you mount optics directly—no milling required, saving you $100–$150 in gunsmith work.
  • Pro: Three 13-round magazines means you’re not hunting for spares at the range.
  • Pro: GLOCK’s Gen4 frame texture gives a secure grip even with sweaty hands or rain.
  • Con: The MOS plate system adds height to the optic—some shooters prefer direct-milled slides for a lower bore axis. If you’re chasing the lowest possible red dot mount, you may want aftermarket slide work.

Comparison: GLOCK 21 V MOS vs. Zev Technologies OZ9 vs. Lone Wolf Distributors Timberwolf

Feature GLOCK 21 V MOS Zev Technologies OZ9 Lone Wolf Distributors Timberwolf
Caliber .45 ACP 9mm (no .45 option) .45 ACP
Slide Cut MOS (proprietary) RMR direct-mill None (buyer mills)
Magazine Capacity 13 rounds 17 rounds (9mm) 13 rounds (GLOCK mags)
Frame Polymer, modular backstraps Aluminum grip module Polymer, GLOCK Gen3 pattern
Price $648.96 $1,200+ $400 (frame only)
Best For Red dot-ready .45 from factory Competition 9mm with low bore axis Budget .45 build with GLOCK parts

The Zev OZ9 is a premium 9mm race gun—no .45 option, and nearly double the price. The Lone Wolf Timberwolf is a frame-only kit that saves money but requires you to source a slide and have it milled for optics. The GLOCK 21 V MOS hits the sweet spot: factory .45 ACP, optics-ready, and under $650.

Frequently Asked Questions

What optics fit the GLOCK 21 V MOS?

The MOS cut accepts GLOCK’s MOS adapter plates. Compatible optics include the Trijicon RMR and SRO, Holosun 407C/507C/508T, Leupold DeltaPoint Pro, and Aimpoint Acro P-1. You’ll need the correct plate (sold separately) for your optic.

Does the GLOCK 21 V MOS come with night sights?

No, the factory fixed sights are white-dot polymer. They’re functional for co-witnessing with a red dot, but many shooters upgrade to steel night sights from Trijicon or Ameriglo for low-light use.

Can I use standard GLOCK 21 magazines in the V MOS?

Yes. The V MOS uses standard GLOCK 21 Gen4 magazines. It ships with three 13-rounders, but any 21-series magazine (13-round or aftermarket 14-round) will work.

Is the GLOCK 21 V MOS California-legal?

No. The GLOCK 21 V MOS is not on the California Roster of Handguns Certified for Sale. It can be purchased by law enforcement or via private-party transfer, but not from a dealer as a new retail sale in CA.

✅ Nationwide delivery (all 50 states, restrictions apply per local laws)
✅ Ships 1–2 business days from order
✅ 30-day returns on unfired, resalable condition
✅ Secure checkout with encrypted payment

Last updated: April 2026

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